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    Cancer cells from a tissue sample can be tested to see which genes are normal and abnormal. The proteins they make can also be tested. HER2 proteins are receptors on breast cells. Normally, HER2 receptors help control how a healthy breast cell grows, divides, and repairs itself. This makes breast cells grow and divide in an uncontrolled way. HER2-positive breast cancers tend to grow faster and are more likely to spread and come back compared to HER2-negative breast cancers. But there are medicines specifically for HER2-positive breast cancers. Chemotherapy is a systemic treatment.

    Powerful drugs can seek out and destroy cancer cells anywhere in the body. HER2-positive breast cancer generally responds well fancer chemotherapy. HER2-positive breast cancer can also be HR-positive. If so, hormone treatments may be an option. Targeted treatments for HER2-positive breast cancer include: Trastuzumab Herceptin helps blocks cancer cells from receiving chemical signals that spur growth. A study of more than 4, women showed that when added to chemotherapy paclitaxel after doxorubicin and cyclophosphamide in early stage HER2-positive breast cancer, trastuzumab resulted in a significant reduction in recurrence and improvement in survival.

    The year survival improved from Results also demonstrated continued improvement of survival without recurrence. The year disease-free survival rate increased from Ado-trastuzumab-emtansine Kadcyla combines trastuzumab with a chemotherapy drug called emtansine. Trastuzumab delivers emtansine directly to the HER2-positive cancer cells.

    Her cancer positive breast 2

    It can be used to shrink tumors and extend survival in women with metastatic breast cancer. Pertuzumab Perjeta is a drug brfast works much like trastuzumab. However, it attaches to a different part of the HER2 protein. Bresst helps determine what you are up against, and how best to treat it. However, research shows that the outlook for a particular breast cancer is more likely to be influenced by the histological type and grade of the breast cancer tumor at the time of discovery. Also, whether or not there is lymphatic involvement is another important factor, and not the hormone receptor status.

    It is true, however, that breast cancer tumors with a positive hormone receptor status have a more indolent course than do hormone receptor-negative tumors. However, the good news is that certain kinds of hormone-receptor positive tumors are actually more responsive to endocrine therapy. So, there is a positive aspect to this as well. This is called a wide local excision WLE. You will need to have radiotherapy after a WLE to make sure any remaining cancer cells are treated. The operation removes the least amount of breast tissue, but leaves a small scar and sometimes a small dent in the breast.

    After a WLE, most women are pleased with the appearance of their breast.

    How your parents spouse in the release will fix on what stage you have: Pursuit to media Criticism for HER2 system breast cancer HER2 competition breast cancer is indicated in a pleaser way to other smart thermostats.

    Removing the breast mastectomy Breast surgeons will usually try cacer remove only part of the breast if possible. But they may recommend you have the whole breast removed if: Surgery to lymph nodes Your surgeon may remove some or all of the lymph nodes in your armpit to check them for cancer cells. This is for two reasons: It gets rid of any cancerous lymph nodes you may need more treatment if only some nodes were removed. It gives information about the stage of the cancer, which helps when making decisions about having other treatments.

    There are different types of lymph node surgery. Your doctor will explain which type they think is most suitable for you.

    Chemotherapy for HER2 positive breast cancer Chemotherapy uses anti-cancer cytotoxic drugs to destroy cancer cells. Chemotherapy can be given in combination with trastuzumab. You may have chemotherapy after surgery to reduce the chances of breast cancer coming back. This is called adjuvant chemotherapy. Some women have chemotherapy before surgery. This is called neo-adjuvant chemotherapy. Chemotherapy given before surgery will reduce the risk of the cancer coming back and it can also shrink the cancer. For example, your doctors may suggest you have a wide local excision instead of a mastectomy.

    There are different groups of chemotherapy drugs. HER2 positive breast cancer is often treated with chemotherapy drugs called anthracylines and taxanes as well as some others. Your doctor or specialist nurse can give you more information about this.

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